USCAP 2020: PANCREATOBILIARY PATHOLOGY COMPANION SOCIETY HANDOUTS

Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract

Moderators:
Martha Bishop Pitman, Deepti Dhall

Speakers:
Jin-Young Jang: Management Algorithms for Pancreatic Cysts and Intraductal Neoplasms: The Surgeon’s Perspective
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Michelle D. Reid: Cytologic Assessment of Cystic/Intraductal Lesions of the Pancreatobiliary Tract
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Aatur D. Singhi: Preoperative Molecular Assessment of Pancreatic Cysts and Intraductal Lesions
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David S. Klimstra: Mucinous Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract
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Irene Esposito: Non-mucinous Cystic Lesions of the Pancreas
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USCAP2020 highlights

Pancreatobiliary Pathology Society Best Abstract Award of USCAP2020 goes to:

Julia R. Naso, MD/PhD
University of British Columbia

Association of Inflammatory Cell Infiltrates with Signatures of Immunogenicity in Pancreatic Adenocarcinoma

See Poster at Tue, March 03 1:00 PM – 4:30 PM
LACC West Exhibit Hall A Poster Board Number: 164
 
 




Message from the President

Dear Pancreatobiliary Pathology Society Members,

Happy Winter!

We are gearing up for the annual USCAP meeting! Our Companion Society session will be held on Saturday, February 29th from 7-10 pm in room LACC 502-A. Our annual Business Meeting will immediately follow. This year is the end of the two-year terms for the Executive Committee so we will be presenting the slate for President, Vice President and Secretary Treasurer. Please attend and cast your votes!  Also, nominations have been submitted for the PBPath Society Abstract Award and the winner will be announced at the Business Meeting.

Our society has been extremely productive over the past several months. The creation of an excellent program for the Companion Society by our Education Committee is only one of several accomplishments. I am excited to inform everyone that Archives of Pathology and Laboratory Medicine is going to publish review articles sponsored by the PBPath Society. These articles are based on the lectures that were given during our Companion Society Meeting at USCAP 2019. Please keep an eye out for these publications. Our Case of the Quarter Subcommittee remains active and has been providing educational cases for all members to tackle; this past fall, we welcomed 4 new members to the subcommittee: Deyali Chatterjee, Goo Lee, Yue Xue and Zhaohai Yang.  Our bimonthly Journal Watch nicely highlights pertinent publications involving the pancreatobiliary tract.

And there is more good news. Because of Serdar Balci’s web-based knowledge and dedication to the society, the Membership/Website Committee, along with the Executive Committee, have appointed Serdar Balci as the official Webmaster for the society – congratulations Serdar on this well-deserved appointment!  The PBPath Society is also now accepting ads for job and fellowship postings.  The Working Groups have been productive as well:  The Cytology group is wrapping-up a multi-institutional study assessing the minimal number of tumor cells required for Ki67 index calculation on pancreas FNA samples using corresponding resections as the gold standard for comparison, and the Neoadjuvant group presented their data at the 2019 USCAP Annual Meeting and is planning to write a consensus paper based on the group’s work. This past fall, PBPath Society members also participated in the ASCP, CAP and European Congress of Pathology annual meetings. Most recently, we’ve been asked to provide input on the ICCR’s draft dataset on carcinoma of the exocrine pancreas (please check your emails as the deadline is February 14th).

Our society continues to be a success because of you, its members! I would like to recognize the following members who continuously contribute time and effort to our society: Olca Basturk, for organizing another stellar USCAP Companion Society session; Serdar Balci for publishing the bimonthly journal watch; Mabel Ko for managing our website and the members of the Executive Committee, Grace Kim, David Klimstra, David Lewin, Volkan Adsay, and Olca Basturk, for keeping everything on track and in order.

The PBPath Society is an international organization that strives to improve the clinical practice of pancreatobiliary pathology by providing an environment of team work and cooperation.  As my Presidency comes to an end, it amazes me how much we have accomplished over the past 2 years.  None of what we now have would have been possible without such collegial, friendly, and motivated members. I am so happy and so proud that I had the chance to serve as the President of this great society.

Alyssa M. Krasinskas, MD


Journal Watch

Happy New Year,

Our latest Journal Watch has just been posted to the PBPS website http://pbpath.org/journal-watch/.

Please share with your colleagues, fellows, and residents.

Pancreatobiliary Pathology Society Education Committee


CASE #5: QUARTER 4, 2019

Clinical details:

74-year-old man presented with jaundice, progressive anemia, dark urine, melena, and a reported weight loss of 10 kilograms in 2 weeks. His comorbidities included mild chronic renal failure, diverticulosis, and dyslipidemia. He was previously a smoker (20 cigs/day, stopped 35 years ago).

On examination, his BMI was 26.1, Hb: 8.7 g/dl, bilirubin total/fractionated (direct): 13.4/8.0 mg/dl, CEA 2.6 U/ml, CA 19-9: 2 U/ml. CT scan showed a 3 cm well-defined lesion in the pancreatic head/periampulla. There was no evidence of distant metastasis. The patient underwent a pancreaticoduodenectomy. 

Gross examination:

The resection specimen was remarkable for a 3 cm well circumscribed, solid mass centered in the pancreatic head, with focal extension to the ampulla, distal bile duct, and peripancreatic adipose tissue. Cut surface was tan white and fleshy.

See figures and answer here Case #5: Quarter 4, 2019


 

USCAP 2020 Abstract Award

Dear Colleagues,
 
We are pleased to announce that the Pancreatobiliary Pathology Society will be awarding a pathology trainee who is presenting an abstract (poster or platform) on the field of pancreatobiliary pathology at the annual meeting of the USCAP. Each abstract will be evaluated based on originality, scientific merit and presentation and the winner will receive a $250 prize. Please remind/encourage your trainees to apply. Applicants do not need to be society member in order to apply.
 
The deadline for the Abstract Awards is January 15, 2020.
 
To submit an application, please email your abstract and the following information to our chair of education committee Dr. Olca Basturk (basturko@mskcc.org)
 
Name:
Training Institute:
Position:
PGY Year:
Date/Time of Presentation:
Abstract Name:
Poster Number (if applicable):
Contact Email:
Comments:
 
PBPS Executive Committee
 

World Pancreatic Cancer Day

November is the Pancreatic Cancer Awareness month and November 21st is World Pancreatic Cancer day.

We, the Pancreatobiliary Pathology Society, support the mission to raise awareness and inspire action on this day.

We send our support to the survivors, their families and to everyone who has lost a loved one to this deadly disease.  We also reiterate our dedication to improve the clinical practice and management of pancreatic cancer and to foster tissue-based research.

World Pancreatic Cancer Day

Spread the word! #WPCD or #worldpancreaticcancerday

-Alyssa


USCAP 2020: PANCREATOBILIARY PATHOLOGY COMPANION SOCIETY PROGRAM

Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract
When: February 29, 2020. 7-10PM
Location: Los Angeles Convention Center

Moderators:
Martha Bishop Pitman
Deepti Dhall

Speakers:
Jin-Young Jang: Management Algorithms for Pancreatic Cysts and Intraductal Neoplasms: The Surgeon’s Perspective
Michelle D. Reid: Cytologic Assessment of Cystic/Intraductal Lesions of the Pancreatobiliary Tract
Aatur D. Singhi: Preoperative Molecular Assessment of Pancreatic Cysts and Intraductal Lesions
David S. Klimstra: Mucinous Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract
Irene Esposito: Non-mucinous Cystic Lesions of the Pancreas

Brief overview of what is being presented/discussed (this will also be shown in the Annual Meeting Program Book):
Despite numerous advances in the field, the diagnosis, classification, grading, and management of cystic and intraductal lesions of the pancreatobiliary tract remain controversial. Additionally, recently described entities such as intraductal tubulopapillary neoplasm (ITPN) and intraductal papillary neoplasm of the bile duct (IPNB) remain diagnostically challenging, and their prognostic implications are poorly understood. The mission of the Pancreatobiliary Pathology Society is to educate surgical and cytopathologists on the importance of the advances in this complex area and will hopefully transform the way we practice pancreatobiliary pathology. The Education Committee, in consultation with Society officers, determined the title, contents, and speakers of this companion meeting.

The chosen topics represent a 360-degree expert evaluation of cystic and intraductal pancreatobiliary lesions in the step-wise manner in which they are often encountered, from the surgeon’s perspective, to their cytomorphologic and molecular characteristics, as well as their histomorphology.


 

Case #4: Quarter 3, 2019

History:

A female in mid-fifties underwent cholecystectomy due to cholelithiasis. No significant previous medical history was noted.

Macroscopy:

Grossly, the gallbladder showed mild wall thickening with the serosa mostly covered with ragged and fibrotic adipose tissue and yellowish calculi. No mass lesion was identified.

The microscopic findings are shown below (Figures 1-4).

See figures and answer here Case #4: Quarter 3, 2019


CASE #3: QUARTER 2, 2019

History:

59 year-old man with a 5.0 cm mass in the head of the pancreas

Pancreaticoduodenectomy:

The patient underwent pancreaticoduodenectomy, which showed a 5.0 cm well circumscribed mass confined in the head of the pancreas. The cut surface of the tumor is tan, soft with mixed areas of necrosis and hemorrhage. The following images (Figure 1-4) are representative micrographs of the tumor.

See figures and answer here CASE #3: QUARTER 2, 2019